Genome editing tools such as CRISPR-Cas9 are reshaping what is possible within the biological sciences. This course will introduce the possibilities of what can be achieved with genome editing, the current limitations, and the fundamentals of how to apply these technologies to enhance the pursuit of targets and therapeutics.
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Scott T. Younger Scott Younger, Ph.D., is the Director of Disease Gene Engineering within the Center for Pediatric Genomic Medicine at Children's Mercy Kansas City. His laboratory is focused on dissecting the molecular mechanisms through which rare genetic variants identified in patients at Children's Mercy lead to disease. Younger joined Children's Mercy from the Broad Institute of MIT and Harvard where his group worked on the development of new methodologies to expand the utility of CRISPR-based genetic screens. Prior to working at the Broad Institute, he completed his postdoctoral studies at Harvard University as an American Cancer Society Fellow. He holds a Ph.D. in cell and molecular biology from UT Southwestern Medical Center. He also received an M.S. in biotechnology from the University of Texas at San Antonio and a B.S.I. in bioinformatics from Baylor University. |
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Samuel A. Hasson, Ph.D. Sam Hasson, Ph.D., is a Senior Scientist and lab head in Amgen Neuroscience (Cambridge, Massachusetts). His lab focuses on the deconvolution of human genetics for novel target selection and employs genome editing technologies to enable this process. A major goal of his work is to identify modulators of complex neuroimmune phenotypes utilizing innovative assay design strategies such as high content screening. Prior to joining Amgen Neuroscience in 2018, Sam led a group in Pfizer Neuroscience. As a postdoc, Sam trained with Richard Youle and Jim Inglese at the National Institutes of Health. |
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